Highlights
- Some of the best Mythic Uniques include Harlequin Crest, Tyrael's Might, and The Grandfather.
- Andariel's Visage is incredible for damage over time builds.
- Ahavarion, Spear of Lycander is more useful than one might expect.
Diablo 4's coveted selection of extremely rare Uniques, commonly referred to as 'Uber Uniques,' have received a proper classification and stat overhaul with Season of the Infernal Hordes. Now called Mythic Uniques, these items offer so much power that they teeter on game-breaking status, but that level of power is why they're so sought after. If you can kill some of the game's toughest bosses, you'll walk away with weapons and armor that are unfathomably strong.
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But as powerful as these items are, Mythic Uniques vary in versatility and general usefulness. Some perform better as stat sticks, while others are so incredibly powerful that they're used in virtually every endgame build. Which items are worth using? Let's find out.
How We Ranked Each Mythic Unique
Our list heavily values usability and general stats over more niche options. Every item on this list is undeniably powerful and has a place in some builds, but the items that tend to be more versatile see more use (notably Harlequin Crest). We mainly focus on:
- Usability in builds.
- How powerful the item is when compared to well-crafted Legendary gear.
- Unique properties that are seldom found elsewhere.
8 Doombringer
The Stat Stick Sword
Doombringer is arguably the worst Mythic Unique in the game, but it's still a good item. This weapon was reworked in Season of the Infernal Hordes to provide tons of maximum life and generic damage reduction, making this a survivability stat stick that fits in the weapon slot. Gaining 35 percent maximum life from a single item is no joke.
Unfortunately, that's all Doombringer has going for it. Its Unique effect is quite lackluster for most builds, struggling to carve a niche when just as many powerful Legendary Aspects exist for every class. Unless you're a Barbarian who can afford to give up a one-handed weapon slot, Legendary weapons generally outperform Doombringer in the damage department.
7 Melted Heart Of Selig
Survivability In One Small Package
Similar to Doombringer, the Melted Heart of Seilg is geared heavily toward builds that need additional survivability and have resources to spare. This amulet greatly increases your character's maximum resource—mana for Sorcerers, fury for Barbarians, essence for Necromancers, et cetera—while simultaneously turning that resource into a secondary bag of health. Whenever you take damage, most of it gets redirected to your resource pool instead.
This item has led to some incredibly strong builds that can tank T120 Pit bosses and Uber Lilith, but this item only works for a select few builds. Any skill that demands high resource drain is fundamentally incompatible with the Melted Heart of Selig, and builds that desperately need survivability can simply use Tyrael's Might instead. Giving up your chest slot is much easier than an amulet.
6 Ahavarion, Spear Of Lycander
Shrines On The Go
Many players consider Ahavarion to be the worst Mythic Unique in the game, but we'd like to push back on this idea slightly. This single weapon gives you:
- 160 percent critical strike, vulnerable, and Overpower damage.
- Most builds can leverage at least two of those damage buckets.
- 33 percent movement speed.
- That's as much movement speed as a well-rolled pair of boots fully masterworked.
- +66 percent to all resistances.
- +18 percent to all stats.
- You are affected by a Shrine 66 percent of the time.
Those aren't minor buffs. The damage buffs alone are absurd and compensate for the spear's otherwise utility-centric affixes. Movement speed is always useful, and extra resistances make gearing significantly easier. Even the percent stat increase is useful for hitting rare node thresholds in your Paragon Board.
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The real reason this staff sees use, though, is its Unique effect. You gain a random shrine effect for 20 seconds upon killing an Elite, triggering a 30-second cooldown. There's certainly an inconsistency with this effect since Shrines in Diablo 4 vary wildly in power, but getting an on-demand Artillery or Channeling Shrine is nothing to scoff at. It certainly pales in comparison to Grandfather or a GG two-handed weapon, but calling Ahavrarion bad is simply not true.
5 Andariel's Visage
The Ultimate Poison Helmet
A somewhat controversial placement, our fifth slot on the list goes to the infectious Andariel's Visage. This helmet offers some strange stats that you don't normally find in this slot, notably attack speed and life on hit. Some builds use Andariel's Visage solely for the massive boost to attack speed, making it easier to hit the 100 percent attack speed cap.
However, the main reason you'd wear Andariel's Visage is to trigger its unique effect. Lucky hits can trigger a poison nova that deals immense damage, one-shotting just about everything in Nightmare Dungeons and Helltide. It's the cornerstone for most damage over time (DoT) builds, and it's a notable favorite for many Rogue players.
So why isn't it higher on the list? Quite simply, it's the lucky hit proc. Not every build can make great use of Andariel's effect because its proc rate varies wildly per build. A Rogue might be able to trigger this multiple times in a few seconds, while a Sorcerer or Druid might struggle to activate it at all. It's not a bad helmet if you aren't specced for DoT damage, but you're missing a key piece of Andariel's appeal if you aren't built to utilize its main perk.
4 Ring Of Starless Skies
A Mythical All-Rounder
Ring of Starless Skies was already a great ring before Season 5, but the Infernal Hordes patch buffed this ring by galactic proportions. It now gives ranks to all Core skills, grants as much critical chance as a Greater Affix Legendary, and significantly buffs your attack speed. It can even solve resource sustain issues for you once its perk is fully ramped up. Spending your resources will build up a massive damage and resource cost reduction boon, stacking up to 50 percent.
There aren't many notable tradeoffs or opportunity costs while wearing this ring. It has virtually every stat you'd want in this slot, and its Unique effect is applicable to virtually every build in the game. Unless your build never consumes resources, the Ring of Starless Skies is always an S-tier pick.
3 The Grandfather
Unwavering Strength
Unless you have advanced tooltips enabled, The Grandfather might seem like a medical weapon at first glance. The notable property of this weapon is that it increases your critical damage by 100 percent, but what isn't clear is that this is multiplicative. You aren't getting a small boost to your additive bucket. All of your critical damage bonus is doubled. If you have over 1,000 percent critical damage, it's now 2,000 percent.
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Every single build in Diablo 4 can leverage this property to great effect, as most builds can spec for critical damage rather easily. That also applies to the item's other affixes, granting bonuses to life, generic damage, and maximum resources. It might not be the most exciting item in Diablo 4, but The Grandfather greatsword is undeniably powerful and highly versatile.
2 Tyrael's Might
Angelic Resistance
Tyrael's Might is now the undisputed champion of damage resistance in Diablo 4. Any build that needs a spike in survivability will use this chest plate. It gives a whopping 20 percent global damage reduction, nearly caps your resistances with an 80 percent resistance roll pre-masterwork, and even raises your maximum resistances by a significant amount. With how resistances work in most ARPGs, gaining max resistance is much stronger than it might seem on paper.
This chest plate also gives you a diet Artillery Shrine while you're at full HP, releasing a barrage of divine arrows at your skill's location. This effect doesn't have a cooldown, but it deals significantly less damage than an Artillery Shrine and doesn't come with any inherent attack speed bonus. Nevertheless, the damage mitigation on offer here is so good that Tyrael's Might is best-in-slot for virtually all builds. The divine barrage is an added bonus.
1 Harlequin Crest
Best In Slot
It should come as no surprise that Harlequin Crest, commonly called by its Diablo 2 moniker "Shako," has taken the top spot. Harlequin Crest was already an S-tier pick before Season of the Infernal Hordes launched, but ever since Blizzard buffed this helmet, it has become a staple in every S-tier meta build worth its salt.
Virtually every build uses this helmet for the 20 percent cooldown reduction it has, which can be raised to 44 percent with perfect masterwork slams (55 if it's a Greater Affix). That's as much cooldown reduction as most min-maxed endgame builds can muster, and that's from a single affix.
Shako also greatly buffs your HP, armor, and maximum resources. It even gives you a global 20% damage reduction buff, much in the same way as Tyrael's Might. And if all of that wasn't enough, the helmet even grants +4 to all skills for your class. That's not a typo; it applies to every skill. The only thing Shako can't do is file your taxes, but if you need to make your Diablo build a meta contender, simply throw on this helmet. Nothing comes remotely close to Harlequin Crest's power. Nothing.
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